Apoptozole

SKU: orb1304341

Description

Apoptozole is a small molecule apoptosis inducer that functions by inhibiting the ATPase activity of Hsc70 and Hsp70. Its application in research includes studying heat shock protein function, endoplasmic reticulum stress, and programmed cell death in both cellular and animal models of cancer.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1054543-47-3
• MW: 625.56
• Purity: 98.02% (May vary between batches)
• Formula: C₃₃H₂₅F₆N₃O₃
• SMILES: COc1ccc(cc1)-c1nc(-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)n(Cc2ccc(cc2)C(N)=O)c1-c1ccc(OC)cc1
• Target: HSP,Apoptosis
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:24 mg/mL (38.37 mM);DMSO:93 mg/mL (148.67 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.28 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ATPase, Apoptosis Activator VII, Apoptozole, Apoptosis, domain, Heat shock proteins, Inhibitor, Hsc70, HSC70, Hsp70, HSP70, HSP, inhibit

Quick Database Links

Gene Symbol

HSP,Apoptosis