APS-2-79 hydrochloride

SKU: orb1300491

Description

APS-2-79 HCl is a small molecule MAPK pathway antagonist that disrupts RAF dimerization and the conformational activation of KSR-bound MEK. It is a valuable research tool for studying oncogenic RAS/MAPK signaling in both cellular and animal models of cancer and developmental disorders.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2002381-31-7
• MW: 423.89
• Purity: 97.08% (May vary between batches)
• Formula: C₂₃H₂₁N₃O₃·HCl
• SMILES: Cl.COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3C)c2cc1OC
• Target: MAPK,MEK
• Solubility: DMSO:90 mg/mL (212.32 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:30 mg/mL (70.77 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

APS 2 79 hydrochloride, APS-2-79 HCl, APS279 hydrochloride, APS-2-79 Hydrochloride, MAP2K, MAPKK, MEK, KSR2, Mitogen-activated protein kinase kinase

Quick Database Links

Gene Symbol

MAPK,MEK