Beclometasone dipropionate

SKU: orb1309679

Description

Beclometasone dipropionate is a synthetic glucocorticoid ester with potent anti-inflammatory and immunomodulatory effects. It acts by binding to nuclear receptors to alter gene expression and suppress pro-inflammatory cytokines. This compound is widely used in research models of asthma, allergic rhinitis, and other inflammatory conditions, both in vitro and in vivo.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 5534-09-8
• MW: 521.04
• Purity: 98.00% (May vary between batches)
• Formula: C₂₈H₃₇ClO₇
• SMILES: [H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)C1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
• Target: ROS,Glucocorticoid Receptor,NO Synthase,Reactive Oxygen Species
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.84 mM);Ethanol:18 mg/mL (34.55 mM);DMSO:55 mg/mL (105.56 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

asthma, Beconase, Beclometasone, Beclometasone dipropionate, Beclometasone Dipropionate, Beclomethasone, Beclomethasone Dipropionate, Beclomethasone dipropionate, Beclovent, 16HBE cells, Inhibitor, iNOS, GlucocorticoidReceptor, Glucocorticoid Receptor, inflammation, inhibit, Vancenase, STAT-1

Quick Database Links

Gene Symbol

ROS,Glucocorticoid Receptor,NO Synthase,Reactive Oxygen Species