Beclomethasone dipropionate

SKU: orb1224685

Description

An anti-inflammatory, synthetic glucocorticoid. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of ASTHMA.(In Vitro):Beclometasone dipropionate (1-100 nM; 20 min) inhibits STAT-1 expression and reduces the levels of iNOS, ROS and NT generated by rhIL-17A in 16HBE cells.(In Vivo):Beclometasone dipropionate (150 μg/kg; nebulization; male BALB/c mice) relieves asthma and decreases total cell number and relative eosinophil number.

Key Properties

• CAS Number: 5534-09-8
• MW: 521.04
• Purity: >98% (HPLC)
• Formula: C₂₈H₃₇ClO₇
• SMILES: CCC(O[C@]1(C(COC(CC)=O)=O)[C@@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C)=O)=O
• Target: GR
• Solubility: DMSO: 10 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Beclomethasone dipropionate | Clenil | Qvar | Beconase | alanase | Vancenase

Quick Database Links

Gene Symbol

GR