Cytarabine

SKU: orb1309161

Description

Cytarabine (Ara-C) is a nucleoside analog DNA synthesis inhibitor with an IC50 of 16 nM. It functions by inhibiting DNA polymerase, leading to cell cycle arrest, autophagy, and apoptosis. This compound is widely used in cancer research, demonstrating antitumor activity in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• CAS Number: 147-94-4
• MW: 243.2
• Purity: >98%
• Formula: C₉H₁₃N₃O₅
• SMILES: O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2
• Target: DNA
• Solubility: Soluble in DMSO (up to 12 mg/ml), or in Water (up to 24 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Arabinocytidine; Cytosine β-D-Arabinofuranoside; U-19920A; Ara-C

Quick Database Links

Gene Symbol

DNA