Epothilone A

SKU: orb1300723

Description

Epothilone A is a microtubule-stabilizing natural product with an EC0.01 of 2 µM. It is used in cancer research to study tubulin polymerization and has demonstrated cytotoxic effects in both in vitro cell-based assays and in vivo tumor models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 152044-53-6
• MW: 493.66
• Purity: 98.27% (May vary between batches)
• Formula: C₂₆H₃₉NO₆S
• SMILES: C[C@H]1CCC[C@H]2O[C@H]2C[C@H](OC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@H]1O)C(\C)=C\c1csc(C)n1
• Target: Microtubule Associated,Apoptosis
• Solubility: Ethanol:92 mg/mL (186.36 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.68 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:92 mg/mL (186.36 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Microtubule Associated, MicrotubuleAssociated, Microtubule/Tubulin, Epo A, epothile, Epothilone A, Apoptosis, Tubulin

Quick Database Links

Gene Symbol

Microtubule Associated,Apoptosis