FRAX597

SKU: orb1301151

Description

FRAX597 is a potent and selective ATP-competitive inhibitor of group I p21-activated kinases (PAKs), demonstrating high inhibitory activity against PAK1, PAK2, and PAK3. This small molecule is a valuable research tool for studying PAK signaling in cancer cell proliferation, invasion, and in vivo tumor models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1286739-19-2
• MW: 558.1
• Purity: 97.34% (May vary between batches)
• Formula: C₂₉H₂₈ClN₇OS
• SMILES: CCn1c2nc(Nc3ccc(cc3)N3CCN(C)CC3)ncc2cc(-c2ccc(cc2Cl)-c2cncs2)c1=O
• Target: PAK
• Solubility: DMSO:13.06 mg/mL (23.4 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FRAX 597, FRAX597, FRAX-597, Inhibitor, p21 activated kinases, inhibit, PAK3, PAK2, PAK, PAK1

Quick Database Links

Gene Symbol

PAK