Grp94 Inhibitor-1

SKU: orb1299961

Description

Grp94 Inhibitor-1 is a highly potent and selective small molecule targeting Grp94 with a 2 nM IC50. This research compound is utilized in vitro and in vivo to study endoplasmic reticulum stress, protein folding, and related pathologies such as cancer and inflammatory diseases.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2234897-35-7
• MW: 352.47
• Purity: 97.02% (May vary between batches)
• Formula: C₂₂H₂₈N₂O₂
• SMILES: CC(C)c1ccc(cc1)-c1ccc(N[C@H]2CC[C@H](O)CC2)c(c1)C(N)=O
• Target: GPCR,HSP
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.67 mM);DMSO:25 mg/mL (70.93 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Heat shock proteins, integrin α2, integrin αL, Grp94, Grp94 Inhibitor 1, Grp94 Inhibitor1, Grp-94 Inhibitor-1, Grp94 Inhibitor-1, HSP

Quick Database Links

Gene Symbol

GPCR,HSP