H3B-5942

SKU: orb1301635

Description

H3B-5942 is a selective estrogen receptor covalent antagonist (SERCA) that irreversibly targets ERα. It is a research tool used in vitro and in vivo to study endocrine-resistant breast cancer models and investigate novel therapeutic strategies for ER-positive malignancies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2052128-15-9
• MW: 494.63
• Purity: ≥95% (May vary between batches)
• Formula: C₃₁H₃₄N₄O₂
• SMILES: CC\C(=C(\c1ccc(OCCNC\C=C\C(=O)N(C)C)cc1)c1ccc2[nH]ncc2c1)c1ccccc1
• Target: Estrogen Receptor/ERR,Estrogen/progestogen Receptor
• Solubility: DMSO:50 mg/mL (101.09 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.04 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EstrogenReceptor, Estrogen Receptor/ERR, H3B 5942, H3B5942, H-3B-5942, H3B-5942, Estrogen Receptor, ERα, ERR, inhibit, Inhibitor, progestogenReceptor, progestogen Receptor

Quick Database Links

Gene Symbol

Estrogen Receptor/ERR,Estrogen/progestogen Receptor