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IM-12

SKU: orb1226948

Description

IM-12 is a novel potent GSK-3β inhibitor with IC50 of 53 nM, significantly increases the β-catenin level and activates canonical Wnt signalling; attenuates cell proliferation of ReNcell VM cells, induces nuclear accumulation of beta-catenin.

Images & Validation

Key Properties

CAS Number1129669-05-1
MW377.4115
Purity>98% (HPLC)
FormulaC22H20FN3O2
SMILESFC(C=C1)=CC=C1CCNC(C2=O)=C(C(N2C)=O)C(C3=C(C=CC=C3)N4)=C4C
TargetGSK-3
SolubilityDMSO: ≥ 54.9 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

IM 12 | IM12

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IM-12 (orb1226948)

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5 mg
$ 90.00
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25 mg
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50 mg
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500 mg
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