Indirubin-3'-monoxime

SKU: orb1302001

Description

Indirubin-3'-monoxime is a potent, cell-permeable small molecule inhibitor of GSK3β (IC50: 22 nM) and several cyclin-dependent kinases (CDKs). It is widely used in biochemical and cellular research to study Wnt/β-catenin signaling, cell cycle progression, and neuronal differentiation in both in vitro and in vivo models.

Research Area

Cardiovascular Research, Cell Biology, Neuroscience, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	160807-49-8
MW	277.29
Purity	>98%
Formula	C₁₆H₁₁N₃O₂
SMILES	ON=C1C(Nc2ccccc12)=C1C(=O)Nc2ccccc12
Target	Kinase
Solubility	Soluble in DMSO (up to 6 mg/ml) or in Ethanol (up to 4 mg/ml).

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Indirubin-3’oxime

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Gene Symbol

Kinase

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