Indirubin-3′-oxime

SKU: orb1298338

Description

Indirubin-3′-oxime is a potent cyclin-dependent kinase (CDK) inhibitor. Research indicates it is implicated in neuronal apoptosis pathways relevant to Alzheimer's disease, making it a valuable tool for in vitro and in vivo studies of neurodegeneration and cell cycle dysregulation.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 667463-82-3
• MW: 277.28
• Purity: 98.26% (May vary between batches)
• Formula: C₁₆H₁₁N₃O₂
• SMILES: O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccccc12
• Target: GSK-3,JNK,CDK
• Solubility: DMSO:55 mg/mL (198.36 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.21 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antiplatelet, chondrocytes, CDK, cdk, collagen, Cyclin dependent kinase, GSK3, GSK-3, Glycogen synthase kinase-3, Glycogen synthase kinase 3, IDR3O, I3O, Inhibitor, MEF2D, inhibit, Indirubin-3'-monoxime, indirubin, Indirubin 3′ oxime, Indirubin3′oxime, Indirubin-3′-oxime, induced, JNK, phosphorylation

Quick Database Links

Gene Symbol

GSK-3,JNK,CDK