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Isosilybin

SKU: orb1303734

Description

Isosilybin and Silybin are potential PXR antagonists for research, aimed at mitigating CYP3A4-mediated drug-drug interactions. Studies in vitro and in vivo support their application in oncology research for improving therapeutic safety by modulating nuclear receptor pathways.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number72581-71-6
MW482.44
Purity98.00% (May vary between batches)
FormulaC25H22O10
SMILESCOc1cc(ccc1O)C1Oc2ccc(cc2OC1CO)C1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O
TargetCytochromes P450
SolubilityChloroform, Dichloromethane, Ethyl Acetate:Soluble;DMSO:88 mg/mL (182.41 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.84 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CYP3A4, Cytochrome P450, Isosilibinin, Isosilybin, Isosilybinin, Q100795, Q 100795

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  • Isosilybin A [orb1218827]

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

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Protocol Information

Isosilybin (orb1303734)

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Available Sizes

Select a size below

1 mg
$ 70.00
5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 150.00
25 mg
$ 270.00
50 mg
$ 470.00
100 mg
$ 670.00
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