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JZL-184

SKU: orb1300664

Description

JZL 184 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor, exhibiting an IC50 of 8 nM for MAGL versus 4 µM for FAAH. This tool compound is widely used in neuroscience research to study endocannabinoid signaling in both in vitro assays and in vivo models.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number1101854-58-3
MW520.50
Purity>98%
FormulaC27H24N2O9
SMILESOC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1
TargetLipase
SolubilitySoluble in DMSO (up to 25 mg/ml).

Storage & Handling

StorageRT
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MAGL, hydrolysis, Inhibitor, neurons, JZL 184, JZL184, JZL-184, Monoacylglycerol lipase, inhibit, analgesia, antinociceptive, 2-Arachidonoylglycerol

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  • JZL184 [orb1222875]

    >98% (HPLC)

    1101854-58-3

    520.49

    C27H24N2O9

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Protocol Information

JZL-184 (orb1300664)

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10 mg
$ 190.00
50 mg
$ 410.00
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