nAChR agonist 1

SKU: orb1309361

Description

DUN71755 is a brain-penetrant and orally active positive allosteric modulator of the α7 nicotinic acetylcholine receptor. This small molecule tool compound is used in research to investigate α7 nAChR function in models of cognitive disorders and neuroinflammation, supporting both in vitro and in vivo experimental studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1394371-75-5
• MW: 419.94
• Purity: 97.17% (May vary between batches)
• Formula: C₂₀H₁₈ClNO₃S₂
• SMILES: CCC(=O)c1sc(c(C)c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1
• Target: AChR
• Solubility: DMSO:120 mg/mL (285.76 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Nicotinic acetylcholine receptors, neuroblastoma, nAChR agonist 1, nAChR, nAChR agonist1, nAChR agonist-1, oral, Inhibitor, inhibit, cognitive, cells, deficits, DUN71755, DUN-71755, DUN 71755, disease, Alzheimer's, brain-permeable, α7 nAChR

Quick Database Links

Gene Symbol

AChR