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Nilotinib

SKU: orb1308331

Description

Nilotinib (AMN107) is an orally bioavailable, potent inhibitor of the Bcr-Abl tyrosine kinase. It demonstrates significant antitumor efficacy in both in vitro and in vivo models and is a key therapeutic agent for research on Imatinib-resistant chronic myelogenous leukemia (CML).

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number641571-10-0
MW529.52
Purity>98%
FormulaC28H22F3N7O
SMILESC(F)(F)(F)C=1C=C(C=C(NC(=O)C2=CC(NC=3N=C(C=CN3)C=4C=CC=NC4)=C(C)C=C2)C1)N5C=NC(C)=C5
TargetKinase
SolubilitySoluble in DMSO (up to 50 mg/ml)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AMN-107

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Quality Guarantee

Quality Guarantee

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Nilotinib (orb1308331)

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10 mg
$ 150.00
50 mg
$ 230.00
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