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Phloretin

SKU: orb1221973

Description

Phloretin is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.

Images & Validation

Key Properties

CAS Number60-82-2
MW274.28
Purity>98% (HPLC)
FormulaC15H14O5
SMILESc1(c(c(cc(c1)O)O)C(=O)CCc1ccc(cc1)O)O
TargetSGLT1| SGLT2
SolubilityDMSO : 50 mg/mL 182.30 mM; H2O : < 0.1 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NSC 407292 | RJC 02792

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  • Phloretin [orb1304838]

    98.53% (May vary between batches)

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    274.27

    C15H14O5

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Phloretin (orb1221973)

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