PI3K-IN-1

SKU: orb1226480

Description

PI3K-IN-1 is a potent inhibitor of PI3K, extracted from patent WO2012103524 A2 and WO2013147649 A2.(In Vitro):PI3K-IN-1 (25 μM) blocks PI3K/Akt signaling pathways. By using the PI3K inhibitor PI3K-IN-1, TGF-β1 induced transformation into myofibroblast is also inhibited, with relatively reduced expressions of α-SMA, Col-1 and Timp-1.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1349796-36-6
• MW: 599.6569
• Purity: >98% (HPLC)
• Formula: C₃₁H₂₉N₅O₆S
• SMILES: O=C(NC1=CC=C(S(=O)(NC2=NC3=CC=CC=C3N=C2NC4=CC(OC)=CC(OC)=C4)=O)C=C1)C5=CC=C(C)C(OC)=C5
• Target: PI3K
• Solubility: DMSO: 27.5 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SAR245409 | Voxtalisib

Quick Database Links

Gene Symbol

PI3K