PI3K-IN-1

SKU: orb1307368

Description

PI3K-IN-1 (Voxtalisib Analogue) is a potent small molecule inhibitor primarily targeting the p110γ isoform of PI3K and mTOR, with additional activity against DNA-PK. This dual inhibitor is utilized in biochemical and cellular research to investigate oncogenic signaling pathways, including in cancer models both in vitro and in vivo.

Research Area

Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 1349796-36-6
• MW: 599.66
• Purity: 97.03% (May vary between batches)
• Formula: C₃₁H₂₉N₅O₆S
• SMILES: COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(NC(=O)c3ccc(OC)c(C)c3)cc2)cc(OC)c1
• Target: DNA-PK,PI3K
• Solubility: DMSO:1 mg/mL (1.67 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.67 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PI3Kγ, PI3Kβ, PI3Kδ, PI3Kα, PI3K, PI3K IN 1, PI3KIN1, PI-3K-IN-1, PI3K-IN-1, XL 765, XL-147 derivative 1, XL765, XL-765, thyroid, SAR245409, SAR-245409, SAR 245409, Voxtalisib Analogue, DNA-PK, DNAPK, fibrosis, extraocular, ophthalmopathy

Quick Database Links

Gene Symbol

DNA-PK,PI3K