Remdesivir

SKU: orb1299527

Description

Remdesivir (GS-5734) is a broad-spectrum antiviral nucleoside analog prodrug that inhibits viral RNA-dependent RNA polymerase. It has demonstrated in vitro and in vivo activity against Ebola, SARS, MERS, and SARS-CoV-2 viruses, supporting its research use for coronavirus and filovirus studies.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1809249-37-3
• MW: 602.58
• Purity: 97.62% (May vary between batches)
• Formula: C₂₇H₃₅N₆O₈P
• SMILES: C(#N)[C@]1(O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OCC(CC)CC)=O)C)=O)[C@@H](O)[C@H]1O)C=3N4C(=CC3)C(N)=NC=N4
• Target: SARS-CoV,DNA/RNA Synthesis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:12.5 mg/mL (20.74 mM);DMSO:240 mg/mL (398.29 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2019-nCoV, antiviral, COVID-19, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, infection, inhibit, Inhibitor, MERS-CoV, GS5734, GS-5734, GS 5734, SARSCoV, SARS coronavirus, SARS-CoV, RNA Synthesis, RNASynthesis, Remdesivir

Quick Database Links

Gene Symbol

SARS-CoV,DNA/RNA Synthesis