Scutellarin

SKU: orb1305016

Description

Scutellarin, a bioactive flavone from Scutellaria baicalensis, suppresses osteoclastogenesis by inhibiting RANKL-induced MAPK and NF-κB pathways and impedes hepatocellular carcinoma (HCC) cell signaling via the STAT3/Girdin/Akt axis. This compound is a valuable research tool for studying bone resorption and liver cancer in vitro.

Research Area

Infectious Disease & Virology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 27740-01-8
• MW: 462.36
• Purity: 95.86% (May vary between batches)
• Formula: C₂₁H₁₈O₁₂
• SMILES: O[C@H]1[C@H](Oc2cc3oc(cc(=O)c3c(O)c2O)-c2ccc(O)cc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O
• Target: Akt,HIV Protease,STAT
• Solubility: DMSO:240 mg/mL (519.08 mM);H2O:insoluble

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Breviscapin, Breviscapine, Breviscapinun, Akt, HIVProtease, HIV, HIV Protease, Scutellarein-7-glucuronide, STAT

Quick Database Links

Gene Symbol

Akt,HIV Protease,STAT