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(+)-Shikonin

SKU: orb1222128

Description

Shikonin is a natural product from the root of Lithospermum erythrorhizon and a specific inhibitor of pyruvate kinase M2 (PKM2). Shikonin also suppresses the ATF2 pathway in skin carcinogenesis.

Images & Validation

Key Properties

CAS Number517-89-5
MW288.3
Purity>98% (HPLC)
FormulaC16H16O5
SMILESCC(C)=CCC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
TargetTMEM16A chloride channel|PKM2|NF-κB|TNF-α
SolubilityDMSO : ≥ 31 mg/mL; 107.53 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Shikonin | Tokyo Violet

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(+)-Shikonin (orb1222128)

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