Sulfasalazine

SKU: orb1310181

Description

Sulfasalazine is a prodrug derived from salicylic acid that exhibits affinity for elastin-rich tissues. It is widely used in research to study ferroptosis and inflammatory pathways, as it inhibits NF-κB, TGF-β, and COX-2 in both cellular and animal models of disease.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 599-79-1
• MW: 398.39
• Purity: >98%
• Formula: C₁₈H₁₄N₄O₅S
• SMILES: OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=N1
• Target: Glutathione
• Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX-2, COX-1, Apoptosis, Antibiotic, Bacterial, Azulfidine, Autophagy, NSC 667219, inhibit, Nuclear factor-κB, Nuclear factor-kappaB, NSC667219, NSC-667219, NF-κB, NFκB, NFkB, NF-kB, Ferroptosis, Inhibitor, Sulfasalazine

Quick Database Links

Gene Symbol

Glutathione