T0901317

SKU: orb1300551

Description

T0901317 is a dual agonist of LXR and FXR with EC50 values of approximately 50 nM and 5 µM, respectively. It also acts as an inhibitor of NF-κB. This small molecule is a valuable research tool for studying nuclear receptor signaling and inflammation in metabolic and liver disease models, both in vitro and in vivo.

Research Area

Cell Biology, Neuroscience

Key Properties

• CAS Number: 293754-55-9
• MW: 481.3
• Purity: >98%
• Formula: C₁₇H₁₂F₉NO₃S
• SMILES: C(C(F)(F)F)(C(F)(F)F)(O)C1=CC=C(N(S(=O)(=O)C2=CC=CC=C2)CC(F)(F)F)C=C1
• Target: Transcription factor
• Solubility: Soluble in DMSO (up to 50 mg/ml) or in ethanol (up to 50 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LDL, HS-68, Inhibitor, FXR, fibroblasts, foreskin, orally, ovarian, LXR, LXRα, LXRβ, inhibit, Liver X Receptor, LiverXReceptor, Liver X receptor, NR1H4, CaOV3, carcinoma, atherosclerosis, Apoptosis, A2780, RAR-related orphan receptor, SKOV3, T0901317, T-0901317, T 0901317, RORα, RORγ, ROR

Quick Database Links

Gene Symbol

Transcription factor