TGR5 Receptor Agonist

SKU: orb1307370

Description

This small molecule is a potent and selective agonist of the TGR5 (GPCR19) receptor. It serves as a key research tool for investigating TGR5's role in metabolic regulation, including glucose homeostasis and energy expenditure, in both in vitro assays and in vivo disease models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1197300-24-5
• MW: 361.22
• Purity: ≥95% (May vary between batches)
• Formula: C₁₈H₁₄Cl₂N₂O₂
• SMILES: CN(C(=O)c1c(C)onc1-c1ccccc1Cl)c1ccc(Cl)cc1
• Target: GPCR19,Calcium Channel
• Solubility: DMSO:50 mg/mL (138.42 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (27.68 mM);Ethanol:100 mM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

diabetes, CCDC, anti-obesity, Calcium Channel, Ca channels, Ca2+ channels, C57BL/6J mice, bladder hypersensitivity, inhibit, Inhibitor, melanophore cells, G protein-coupled Bile Acid Receptor 1, G-protein coupled receptor 19, GPBAR1, GPCR19, U2-OS cells, TGR5 Receptor Agonist, TGR-5 Receptor Agonist, TGR5 Receptor Agonist, TGR5

Quick Database Links

Gene Symbol

GPCR19,Calcium Channel