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Tofacitinib

SKU: orb1300872

Description

Tofacitinib (Tasocitinib) is an orally bioavailable Janus kinase (JAK) inhibitor with selectivity for JAK3, JAK2, and JAK1. It is a research compound applied in studies of rheumatoid arthritis and other immune-mediated diseases, utilizing both in vitro cellular assays and in vivo animal models to investigate JAK-STAT signaling pathways.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number477600-75-2
MW312.4
Purity>98%
FormulaC16H20N6O
SMILESC[C@@H]1CCN(C[C@@H]1N(C)C1=C2C=CNC2=NC=N1)C(=O)CC#N
TargetKinase
SolubilitySoluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Tasocitinib; CP-690550

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Tofacitinib (orb1300872)

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5 mg
$ 190.00
25 mg
$ 380.00
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