Ursodeoxycholic acid

SKU: orb1310372

Description

Ursodeoxycholic acid (UDCA) is a research compound known for its potent inhibition of the hepatic fatty acid transporter FATP5. It is widely used in studies investigating cholesterol metabolism, gallstone dissolution, and liver diseases, with applications in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 128-13-2
• MW: 392.57
• Purity: ≥95% (May vary between batches)
• Formula: C₂₄H₄₀O₄
• SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
• Target: GPCR19,Potassium Channel,FXR,Angiotensin-converting Enzyme (ACE),Endogenous Metabolite
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:73 mg/mL (185.95 mM);DMSO:255 mg/mL (649.57 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.74 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bile salt export pump, FXR, G protein-coupled Bile Acid Receptor 1, G-protein coupled receptor 19, GPCR19, GPBAR1, EndogenousMetabolite, Endogenous Metabolite, Inhibitor, gastrointestinal diseases, hepatic, oral, inhibit, intestinal barrier integrity, NR1H4, lipid metabolism, PotassiumChannel, Potassium Channel, secondary bile acid, UDCA, Ursodeoxycholate, Ursodiol, Ursodeoxycholic acid, UDCS, TGR5

Quick Database Links

Gene Symbol

GPCR19,Potassium Channel,FXR,Angiotensin-converting Enzyme (ACE),Endogenous Metabolite