VER-49009

SKU: orb1304188

Description

VER-49009 (CCT 129397) is a highly potent small molecule inhibitor of Hsp90, exhibiting an IC50 of 25 nM and a Kd of 78 nM. It is a valuable research tool for studying oncogenic client protein degradation and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 558640-51-0
• MW: 387.82
• Purity: 99.36% (May vary between batches)
• Formula: C₁₉H₁₈ClN₃O₄
• SMILES: CCNC(=O)c1n[nH]c(c1-c1ccc(OC)cc1)-c1cc(Cl)c(O)cc1O
• Target: HSP
• Solubility: DMSO:100 mg/mL (257.85 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.31 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CCT 129397, CCT129397, CCT-129397, Heat shock proteins, Hsp90, HSP, Inhibitor, inhibit, VER49009, VER-49009, VER 49009

Quick Database Links

Gene Symbol

HSP