YUM70

SKU: orb1218039

Description

YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.

Key Properties

• CAS Number: 423145-35-1
• MW: 398.84
• Purity: >98% (HPLC)
• Formula: C₂₁H₁₉ClN₂O₄
• SMILES: O=C(CCC)NC(C1=CC=C2C(OCO2)=C1)C(C=C(Cl)C3=C4N=CC=C3)=C4O
• Target: GPR
• Solubility: DMSO:100 mg/mL (250.73 mM; Need ultrasonic)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GPR