YUM70

SKU: orb1298541

Description

YUM70 is a potent and selective GRP78 inhibitor (IC50 = 1.5 μM) that induces ER stress and apoptosis in pancreatic cancer cells. It serves as a valuable chemical probe for studying ER stress mechanisms and apoptosis in both in vitro and in vivo cancer research models.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 423145-35-1
• MW: 398.84
• Purity: 97.25% (May vary between batches)
• Formula: C₂₁H₁₉ClN₂O₄
• SMILES: CCCC(=O)NC(c1ccc2OCOc2c1)c1cc(Cl)c2cccnc2c1O
• Target: HSP,Apoptosis,GPCR
• Solubility: DMSO:100 mg/mL (250.73 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, cancer, Heat shock proteins, Inhibitor, glucose-regulated, GRP78, HSP, endoplasmic, inhibit, pancreatic, stress-mediated, reticulum, protein, YUM 70, YUM70, YUM-70

Quick Database Links

Gene Symbol

HSP,Apoptosis,GPCR