Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Irinotecan

SKU: orb1300959

Description

Irinotecan (CPT-11) is a camptothecin-derived topoisomerase I inhibitor used in cancer research. It induces lethal double-strand DNA breaks by stabilizing the Topo I-DNA complex. This mechanism underpins its application in studying colorectal and other cancers in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number97682-44-5
MW586.68
Purity98.00% (May vary between batches)
FormulaC33H38N4O6
SMILESCCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12
TargetAutophagy,Topoisomerase
SolubilityDMSO:11 mg/mL (18.75 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.2 mg/mL (5.45 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, Irinotecan, CPT 11, CPT11, CPT-11, Autophagy, (+)-Irinotecan, Topoisomerase, Topo I, Topotecin

Similar Products

  • SN-38 [orb1307686]

    >98%

    86639-52-3

    392.41

    C22H20N2O5

  • Irinotecan Hydrochloride [orb1310566]

    98.00% (May vary between batches)

    100286-90-6

    623.14

    C33H39ClN4O6

  • Irinotecan HCl [orb1310567]

    >98%

    136572-09-3

    586.69 ∙ 36.46 ∙ 54.05

    C33H38N4O6 ∙ HCl ∙ 3H20

  • Aurantio-obtusin [orb1300205]

    98.05% (May vary between batches)

    67979-25-3

    330.29

    C17H14O7

Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download
MSDS
Safety Data Sheet
Download

Request a Document

Protocol Information

Irinotecan (orb1300959)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Available Sizes

Select a size below

10 mg
$ 70.00
25 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
50 mg
$ 100.00
100 mg
$ 130.00
200 mg
$ 170.00
500 mg
$ 270.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry