Ritonavir

SKU: orb1308324

Description

Ritonavir (ABT-538) is a peptidomimetic inhibitor of HIV-1 and HIV-2 proteases. While its own antiviral activity is limited by serum protein binding, it is widely used in research, both in vitro and in vivo, as a potent cytochrome P450 inhibitor to pharmacokinetically boost other protease inhibitors.

Research Area

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 155213-67-5
• MW: 720.9
• Purity: >98%
• Formula: C₃₇H₄₈N₆O₅S₂
• SMILES: CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CN=CS1)CC1=CC=CC=C1
• Target: Cytochrome/MDR
• Solubility: Soluble in DMSO (12 mg/ml with warming) or in ethanol (5mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ABT538, ABT-538, ABT 538, Abbott 84538, A 84538, A84538, A-84538, Apoptosis, HIVProtease, HIV Protease, HIV, Human immunodeficiency virus, Inhibitor, inhibit, Ritonavir, RTV, SARS-CoV, SARSCoV, SARS coronavirus

Quick Database Links

Gene Symbol

Cytochrome/MDR