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Sorafenib

SKU: orb1310944

Description

Sorafenib is an orally active multikinase inhibitor targeting Raf, VEGFR, PDGFRβ, and others, with IC50 values in the nanomolar range. It exhibits antitumor activity by inducing apoptosis, autophagy, and ferroptosis, making it a valuable tool for cancer research in both cellular and animal models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number284461-73-0
MW464.83
Purity>98%
FormulaC21H16ClF3N4O3
SMILESO(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2
TargetKinase
SolubilitySoluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BAY 43-9006

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Sorafenib (orb1310944)

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10 mg
$ 160.00
50 mg
$ 300.00
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