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Osimertinib

SKU: orb1305406

Description

Osimertinib (AZD-9291) is an oral, irreversible third-generation EGFR inhibitor designed to target the T790M resistance mutation in non-small cell lung cancer (NSCLC). It is widely used in preclinical research, demonstrating potent antitumor activity in both in vitro cell assays and in vivo xenograft models of EGFR-mutant NSCLC.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1421373-65-0
MW499.6
Purity>98%
FormulaC28H33N7O2
SMILESCN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4)=NC=C3
TargetKinase
SolubilitySoluble in DMSO (up to 40 mg/ml)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AZD-9291

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Quality Guarantee

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Osimertinib (orb1305406)

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10 mg
$ 170.00
50 mg
$ 290.00
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